Amphicampa valves are asymmetric to the apical axis and symmetric to the transapical axis. Both the dorsal and ventral margins of the valves are undulate. The raphe is very short and restricted to the valve ends. The raphe may only be visible through the thickening of the helictoglossa.
A single species, A. eruca Ehrenberg, is found in circumneutral to alkaline waters in the midwest and western United States. This species has also been found in subfossil pothole deposits in Iowa (Julius, unpublished data).