Cyclotella distinguenda has smaller valves, a lower stria density and the central area covers 1/3 to 1/2 of the valve face. Cyclotella gamma has 1-2 distinct central fultoportulae, uniseriate striae and the central area covers 1/2 of the valve face. Cyclotella meneghiniana has smaller valves, more distinct alveolae and the central area covers 1/3 to 1/2 of the valve face. Cyclotella agassizensis has smaller valves, a lower stria density and small, submarginal spines.