Cyclotella comensis has valves that are tangentially undulate, with secondary radial undulation.
Cyclotella tripartita similarly has ornamentation in three wedge-shaped groups, but its valve face is radially undulate.
Cyclotella kuetzingiana and C. krammeri have much smaller central areas, with irregular, occasionally bifurcating striae giving the central area perimeter a 'ragged' appearance.
Cyclotella ocellata may be difficult to distinguish. In general, C. ocellata shows 3 (sometimes 4-6) deep, concentric depressions and may have 3 large papillae or silica ‘balls’ on the valve face.
BioData Reference
Houk et al. 2010 Pl 210 Figs 1-25