Neidium sacoense has smaller valves and more cuneate apices.
Neidium fossum has a broader central area and one broad longitudinal canal with associated smaller canals on each side of the valve.
Neidium dilatatum has smaller, more rounded areolae, and larger valves.
Neidium amphigomphus var. obtusum has an elliptical valve outline.
Neidium amphigomphus f. curtum is a species belonging to the genus Luticola and has triundulate valve margins.
Neidium iridis is typically larger, and has a row of irregular depressions on one side of the raphe.